Bishop Zumarraga was a saintly man, very just and compassionate. He built the first hospital, library and university in the Americas. He also was the Protector of the Indians, entrusted by Emperor Charles V to enforce his decree issued in August 1530, stating, "No person shall dare to make a single Indian a slave whether in war or in peace. Whether by barter, by purchase, by trade, or on any other pretext or cause whatever." (Note that in 1537 Pope Paul III condemned and forbade the enslavement of the Native American Indian.) However, Bishop Zumarraga listened patiently to Juan Diego, and said he would reflect on the matter, understandably doubting such a story.whole article at Catholic Education
Juan Diego went back to Tepayac and reported the bishop's response. Mary instructed him to try again. So the next day, he did. Although this time it was more difficult to see the bishop, Juan Diego prevailed, and the bishop once more listened patiently. However, the bishop asked him to bring back a sign from Mary to prove the story. Again, Juan Diego reported the matter to our Blessed Mother, who told him to return the next day to receive "the sign" for the bishop.
On December 11, Juan Diego spent the day caring for his very sick uncle, Juan Bernardino. He asked Juan Diego to go and bring a priest who would hear his confession and administer the last rites. On December 12, Juan Diego set out again, but avoided Tepeyac Hill because he was ashamed that he had not returned the previous day as our Blessed Mother had requested. While making his detour, the Blessed Mother stopped him and said, "Hear and let it penetrate into your heart, my dear little son: let nothing discourage you, nothing depress you. Let nothing alter your heart or your countenance. Also, do not fear any illness or vexation, anxiety or pain. Am I not here who am your mother? Are you not under my shadow and protection? Am I not your fountain of life? Are you not in the folds of my mantle, in the crossing of my arms? Is there anything else that you need?" Mary reassured Juan Diego that his uncle would not die; in fact, his health had been restored.